Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300050 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 6 Pages |
Abstract
⺠Effect of cholesterol on antimicrobial peptide induced membrane disruption in different lipid phases was tested. ⺠Cholesterol had no effect on the AMP-induced membrane disruption in liquid disordered phase. ⺠Formation of liquid ordered phase by cholesterol strongly inhibited membrane disruption by an AMP. ⺠Cholesterol had no effect on the disruption of raft membranes with liquid ordered-liquid disordered coexistence.
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Authors
Austin J. McHenry, Michele F.M. Sciacca, Jeffrey R. Brender, Ayyalusamy Ramamoorthy,