| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8300089 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 9 Pages |
Abstract
⺠We study voltage sensitivity and deactivation rates at histamine H3 and H4 receptors. ⺠Histamine potency in a channel activation assay is decreased by depolarization. ⺠The potency decrease is more pronounced at hH3445 than at hH3365 and H4 receptors. ⺠Rates of deactivation upon agonist washout differ between the histamine receptors. ⺠The hH3365 receptor deactivates about 5 times slower than the hH3445 receptor.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Kristoffer Sahlholm, Johanna Nilsson, Daniel Marcellino, Kjell Fuxe, Peter Ã
rhem,