Article ID Journal Published Year Pages File Type
8300117 Biochimica et Biophysica Acta (BBA) - Biomembranes 2011 8 Pages PDF
Abstract
► We studied the phosphatidylserine (PS) distribution during RBC maturation and aging.► Blood, bone marrow and cultured human and murine erythroid cells were studied. ► PS externalization/shedding decreased during maturation but increased during aging. ► PS externalization and shedding were regulated by changes in the cellular Ca flux. ► We suggest that this redistribution plays a role in RBC maturation and senescence.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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