Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300117 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 8 Pages |
Abstract
⺠We studied the phosphatidylserine (PS) distribution during RBC maturation and aging.⺠Blood, bone marrow and cultured human and murine erythroid cells were studied. ⺠PS externalization/shedding decreased during maturation but increased during aging. ⺠PS externalization and shedding were regulated by changes in the cellular Ca flux. ⺠We suggest that this redistribution plays a role in RBC maturation and senescence.
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Authors
Inna Freikman, Eitan Fibach,