Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300137 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 9 Pages |
Abstract
⺠We study the impact of oleic acid to the assembly of stratum corneum model membranes. ⺠Deuterium-labeling is used to localize oleic acid inside the membrane. ⺠The presence of oleic acid is associated with a significant loss of lamellar order. ⺠Perturbation of lipid assembly is crucial for penetration enhancer activity of oleic acid.
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Authors
Tanja N. Engelbrecht, Annett Schroeter, Thomas HauÃ, Reinhard H.H. Neubert,