Article ID Journal Published Year Pages File Type
8300137 Biochimica et Biophysica Acta (BBA) - Biomembranes 2011 9 Pages PDF
Abstract
► We study the impact of oleic acid to the assembly of stratum corneum model membranes. ► Deuterium-labeling is used to localize oleic acid inside the membrane. ► The presence of oleic acid is associated with a significant loss of lamellar order. ► Perturbation of lipid assembly is crucial for penetration enhancer activity of oleic acid.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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