Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300138 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 12 Pages |
Abstract
⺠TRPC6 proteins form cation channels found in many tissues and organs. ⺠The over-expression of TRPC6 channels causes an intracellular accumulation of Zinc. ⺠The entry of Zn2+ through TRPC6 regulates the size of internal pools of Zn2+. ⺠Our data unveil an unanticipated role of TRPC6 in cellular zinc homeostasis.
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Authors
Julien Gibon, Peng Tu, Sylvain Bohic, Pierre Richaud, Josiane Arnaud, Mike Zhu, Guylain Boulay, Alexandre Bouron,