| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8300151 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 8 Pages |
Abstract
⺠Newborn mammals have saturated 3O-acyl sphingomyelins in their plasma. ⺠We made 3O-palmitoyl palmitoylsphingomyelin and studied its membrane properties. ⺠The SM analog formed highly ordered domains in fluid bilayers. ⺠Cholesterol was able to interact with the SM analog, and formed liquid-ordered phase. ⺠We speculate that 3O-acyl SM is important in membranes as a super-ordered lipid.
Keywords
MβCD1-palmitoyl-2-stearoyl-(7-doxyl)-sn-glycero-3-phosphocholine7SLPCcholestatrienolTX100DPHPoPCPSMDSCLaurdan4-dimethylaminopyridinetPADMAPCTL1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine1,6-diphenyl-1,3,5-hexatrienesphingomyelinTriton X-100phosphatidylcholineFluorescence spectroscopyDifferential scanning calorimetry
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Authors
Christian Sergelius, J. Peter Slotte,