Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300189 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 10 Pages |
Abstract
⺠Extracellular organic/inorganic anions increase/decrease P2X7 receptor activation. ⺠Extracellular anions modify gating of P2X7 receptors via an allosteric binding site. ⺠Anions change open probability of P2X7R channels by affecting their shut times. ⺠Anions do not change P2X7R pore properties. âºThe P2X7R is not anion permeable.
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Authors
Christoph Kubick, Günther Schmalzing, Fritz Markwardt,