| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8300511 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2013 | 9 Pages |
Abstract
⺠The eukaryotic exosome is a major ribonuclease for RNA decay and processing. ⺠The repertoire of catalytic subunits varies among Eukaryota. ⺠Some catalytic subunits are compartment-specific and give rise to exosome isoforms. ⺠Substrate threading modulates ribonuclease activities in the holocomplex. ⺠The many cellular functions of the exosome are mediated by auxiliary factors.
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Authors
Aleksander Chlebowski, MichaÅ Lubas, Torben Heick Jensen, Andrzej Dziembowski,