Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300596 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2012 | 13 Pages |
Abstract
⺠CDKL5 enhances neuronal differentiation. ⺠CDKL5 arrests cell cycle of neuronal precursor cells. ⺠MYCN directly represses transcription of CDKL5. ⺠These results may help explain the neurological symptoms of RTT patients.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Emanuele Valli, Stefania Trazzi, Claudia Fuchs, Daniela Erriquez, Renata Bartesaghi, Giovanni Perini, Elisabetta Ciani,