Article ID Journal Published Year Pages File Type
8300603 Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2012 9 Pages PDF
Abstract
► Myogenin was identified as a novel αNAC target gene. ► αNAC interacts with the corepressors HDAC1 and HDAC3. ► αNAC recruits HDAC1/3 to the promoter of silent, but not expressed, target genes. ► A mutant αNAC not interacting with HDACs cannot inhibit Myogenin or myogenesis. ► We propose new roles for αNAC in transcriptional control during differentiation.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , ,