Article ID Journal Published Year Pages File Type
8300615 Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2012 9 Pages PDF
Abstract
► Mitochondrial (mt) RNA polymerases (RNAP) serve as an intriguing link between single and multi-subunit RNAPs. ► Although structurally similar to T7 RNAP, the mt RNAPs depend on accessory transcription factors. ► Both components bind the promoter and work cooperatively to catalyze promoter-specific initiation. ► Induced-fit mechanism involving DNA bending is employed to differentiate between promoter and non-promoters.
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