Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300615 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2012 | 9 Pages |
Abstract
⺠Mitochondrial (mt) RNA polymerases (RNAP) serve as an intriguing link between single and multi-subunit RNAPs. ⺠Although structurally similar to T7 RNAP, the mt RNAPs depend on accessory transcription factors. ⺠Both components bind the promoter and work cooperatively to catalyze promoter-specific initiation. ⺠Induced-fit mechanism involving DNA bending is employed to differentiate between promoter and non-promoters.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Aishwarya P. Deshpande, Smita S. Patel,