Article ID Journal Published Year Pages File Type
8300630 Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2012 13 Pages PDF
Abstract
► Mitochondrial DNA is susceptible to endogenous and environmental damage. ► Mitochondria lack the full cohort of nuclear DNA repair mechanisms. ► Persistent mtDNA damage poses a threat to mitochondrial gene expression. ► Mitochondrial polymerase disruption by mtDNA damage may underlie human disease and environmental toxicity.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
,