Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300636 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2012 | 10 Pages |
Abstract
⺠Mitochondrial homeostasis is maintained by PNPASE from an intermembrane space location. ⺠PNPASE activities in mitochondrial RNA import and RNA processing are separable. ⺠Imported RNAs are required for mitochondrial genome replication, transcription, and translation. ⺠PNPASE regulation of mitochondrial metabolism and RNA import are thus far inseparable.
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Authors
Geng Wang, Eriko Shimada, Carla M. Koehler, Michael A. Teitell,