Article ID Journal Published Year Pages File Type
8300665 Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2012 5 Pages PDF
Abstract
► Higher mtDNA mutation rate enforces co-evolution with nuclear DNA encoded factors. ► Disruption of mito-nuclear co evolution affects diseases, evolutionary processes. ► Such co-evolution affects interactions of proteins, protein-RNA and protein-DNA. ► Co evolution plays an important role in modulating mitochondrial activity.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Mitochondrial-nuclear co-evolution and its effects on OXPHOS activity and regulation
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