Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300677 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2018 | 8 Pages |
Abstract
The assembly of PDE5 in tetramers in platelets, beside the dimers, opens the possibility to alternative assembly/allosteric regulation of this enzyme, as component of large signaling complexes, in all cellular districts in which PDE5 is present.
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Authors
Silvia Cardarelli, Adriana Erica Miele, Carlotta Zamparelli, Stefano Biagioni, Fabio Naro, Francesco Malatesta, Mauro Giorgi, Michele Saliola,