| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8300680 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2018 | 11 Pages |
Abstract
In S. salar, activation of TLR5M and TLR5S is dependent on MyD88 as an adaptor protein after stimulation with flagellin. A sequential mechanism of activation, amplification and attenuation of the TLR5M/flagellin signalling pathway is proposed for this species. Our mathematical model is a robust predictive tool for generating new hypotheses about TLRs in S. salar.
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Authors
Muñoz-Flores C., Astuya A., Roa F.J., Romero A., Acosta J., Sánchez O., Toledo J.R.,