Crystal structure and substrate specificity of ExoY, a unique T3SS mediated secreted nucleotidyl cyclase toxin from Pseudomonas aeruginosa

Article ID	Journal	Published Year	Pages	File Type
8300733	Biochimica et Biophysica Acta (BBA) - General Subjects	2018	14 Pages	PDF

Keywords

RMSD CIMP TAK1 CTP UTP Vibrio vulnificus DLS cGMP T3SS ITC IPTG NTA cNMP SEC GTP cCMP ExoY inosine 3′,5′-cyclic monophosphate uridine 3′,5′-cyclic monophosphate cAMP guanosine 3′,5′-cyclic monophosphate adenosine 3′,5′-cyclic monophosphate Adenosine Triphosphate ATP edema factor nitrilotriacetic acid SDS-PAGE Sodium dodecyl sulfate polyacrylamide gel electrophoresis Size-exclusion chromatography Uridine triphosphate X-ray crystallography cUMP molecular replacement Molecular dynamics Pseudomonas aeruginosa cytidine 3′,5′-cyclic monophosphate Cytidine triphosphate root mean square deviation Dynamic Light Scattering Isothermal calorimetry Guanosine triphosphate

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Crystal structure and substrate specificity of ExoY, a unique T3SS mediated secreted nucleotidyl cyclase toxin from Pseudomonas aeruginosa

Authors

Basavraj Khanppnavar, Saumen Datta,