Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300785 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2018 | 34 Pages |
Abstract
Long IDRs occur in about 50% of human proteins. They are poorly characterized despite much recent attention. Our results suggest the importance of a subtle balance between PreSMo stability and IDR activity, which may provide a novel target for future pharmaceutical intervention.
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Authors
Evdokiya Salamanova, Joana Costeira-Paulo, Kyou-Hoon Han, Do-Hyoung Kim, Lennart Nilsson, Anthony P.H. Wright,