Article ID Journal Published Year Pages File Type
8300898 Biochimica et Biophysica Acta (BBA) - General Subjects 2018 50 Pages PDF
Abstract
Phosphorylation of Thr177 could activate CDK6 by lowering its state transition barrier form open to closed state, while the binding preferences of three types of CDK6 inhibitors vary.187
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Reduced state transition barrier of CDK6 from open to closed state induced by Thr177 phosphorylation and its implication in binding modes of inhibitors
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