Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300946 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2018 | 47 Pages |
Abstract
For living systems, the dynamic assembly and disassembly of macromolecular complexes is of utmost importance for cellular homeostasis and, if dysregulated, implied in human disease. It is thus instructive for the advancement of the study of the dynamical ordering to discuss the potential possibilities of solution NMR spectroscopy and its applications. This article is part of a Special Issue entitled “Biophysical Exploration of Dynamical Ordering of Biomolecular Systems” edited by Dr. Koichi Kato.
Keywords
MaxEntMDDHSQCSAILGAFHEKIDPPDBEROsHPRMBPGb3SIFTNOEIn-cell NMRLBTCPMGmulti-dimensional decompositionCCRNUSR1ρCPPsolution NMR spectroscopynuclear magnetic resonanceChemical shift anisotropyCarr-Purcell-Meiboom-GillH/DLongitudinal relaxationTransverse relaxationCross-correlated relaxationenzyme IResidual dipolar couplingStreptolysin Osloamyotrophic lateral sclerosisparamagnetic relaxation enhancementCSAModel-freeChoStable isotope labellingALSTATModel-free analysisTROSYtrans-activating transcriptional activatorTractNMRMaximum EntropyDeSTDynamicsMolecular dynamicsPCsRexSODChinese hamster ovary cellshuman embryonic kidney cellsCompressed sensingSuperoxide dismutaseRdcRadio-frequencypreSmileeffective transverse relaxation rateNon-uniform samplinghydrogen/deuteriumMFARelaxation dispersionProtein Data BankMaltodextrin-Binding ProteinIntrinsically disordered proteincell penetrating peptideheteronuclear single quantum coherence
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Teppei Ikeya, David Ban, Donghan Lee, Yutaka Ito, Koichi Kato, Christian Griesinger,