Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8301160 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 10 Pages |
Abstract
⺠S phase entry is correlated with a marked decrease of O-GlcNAc modified proteins ⺠O-GlcNAcase activity increases at the G1/S transition ⺠Identification of 58 differentially putative O-GlcNAcylated proteins during G1/S transition ⺠We report cell-cycle dependent O-GlcNAcylation of nucleoplasmic DNA licensing factors MCMs ⺠O-GlcNAcylation may regulate DNA replication initiation
Keywords
MCMMCM proteinCaprin-1OGAUDP-GlcNAcO-GlcNAc transferaseO-GlcNAcCDKOGThnRNPCHXPRBPTMuridine diphosphate N-acetylglucosaminepost-translational modificationG1/S transitionpost-translational modificationsheterogeneous nuclear ribonucleoproteincytokeratincycloheximideminichromosome maintenanceHydroxyurearetinoblastoma proteincyclin dependent kinase
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Authors
Ludivine Drougat, Stéphanie Olivier-Van Stichelen, Marlène Mortuaire, François Foulquier, Anne-Sophie Lacoste, Jean-Claude Michalski, Tony Lefebvre, Anne-Sophie Vercoutter-Edouart,