Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8301183 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 7 Pages |
Abstract
⺠First rabbit Fab crystal structure ⺠First structure of a conformation-dependent, amyloid oligomer specific antibody ⺠Structure shows disulfide bonds unique to rabbit IgG. ⺠The data rule out steric zipper formation as the Fab antigen-binding mechanism.
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Authors
Hiromi Arai, Charles Glabe, Hartmut Luecke,