| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8301203 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 10 Pages |
Abstract
⺠A role of non-traditional plasma heme scavengers is evaluated. ⺠Human α1-PI and Hp are examined for binding with heme, PPIX and BR. ⺠Methods include UV/Vis, fluorescence, SPR, CD and functional assays. ⺠This study for the first time defines human α1-PI as a heme binding protein. ⺠Affinity of α1-PI to heme is of the same order of magnitude as that of albumin.
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Authors
Elena Karnaukhova, Sonia Silinsky Krupnikova, Mohsen Rajabi, Abdu I. Alayash,