| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8301214 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 10 Pages |
Abstract
⺠INDO increases Ca2 + concentrations first in cytosol and then in mitochondria. ⺠Inhibitors of IP3R and RyR receptors prevent the INDO induced caspases activation. ⺠Polyphenols prevent the Ca2 + mobilization induced by INDO. ⺠Quercetin prevents cytotoxicity, apoptosis and caspases activation induced by INDO.
Keywords
2-aminoethoxydiphenyl borateRyRMPTPRESIP3R2-APBSOCCEGTANSAIDRFURUTinositol trisphosphate receptorsMMPDMSOPpsethylene glycol tetraacetic acidmitochondrial permeability transition poreIndomethacinQueApoptosisnonsteroidal anti-inflammatory drugGastrointestinaldimethylsulphoxideResveratrolendoplasmic reticulumSociSERCARutinindorelative fluorescence unitMitochondrial membrane potentialPolyphenolsQuercetinRyanodine receptors
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Authors
Catalina Carrasco-Pozo, Edgar Pastene, Carola Vergara, Moises Zapata, Cristian Sandoval, Martin Gotteland,