Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8301226 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2018 | 17 Pages |
Abstract
This review describes the cell biology of this model and critically assesses its application as a marker of cardiovascular risk. We describe the pathways for cell cholesterol export, current cell models used in the CEC assay with their limitations and consider the contribution that measurement of serum CEC provides to our understanding of HDL function in vivo.
Keywords
CLA-1ABCG1apoBApoA-IABCA1CETPACATCACCECcAMPAdenosine TriphosphateATPCyclic adenosine monophosphateApoeApolipoprotein A-IApolipoprotein Bapolipoprotein Ecoronary artery diseasecardiovascular diseasecomputed tomographyCVDCADCholesterol efflux capacitycholesterol ester transfer proteincholesteryl esterfree cholesterolcoronary artery calcium
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Authors
Malcolm Anastasius, Celine Luquain-Costaz, Maaike Kockx, Wendy Jessup, Leonard Kritharides,