A bidirectional crosstalk between glioblastoma and brain endothelial cells potentiates the angiogenic and proliferative signaling of sphingosine-1-phosphate in the glioblastoma microenvironment

Article ID	Journal	Published Year	Pages	File Type
8301229	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2018	14 Pages	PDF

Keywords

DMEM FBS dulbecco modified Eagle's medium SphK SPH HPTLC S1PRs ERK GEC BECs GBM S1P BSA bovine serum albumin Sphingosine kinase Sphingosine kinase 2 Sphingosine-1-phosphate sphingosine fetal bovine serum brain endothelial cells Endothelial cells Glioblastoma cells Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)high-performance thin layer chromatography extracellular signal-regulated kinase Glioblastoma

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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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A bidirectional crosstalk between glioblastoma and brain endothelial cells potentiates the angiogenic and proliferative signaling of sphingosine-1-phosphate in the glioblastoma microenvironment

Authors

Loubna Abdel Hadi, Viviana Anelli, Laura Guarnaccia, Stefania Navone, Matteo Beretta, Francesco Moccia, Cristina Tringali, Vasile Urechie, Rolando Campanella, Giovanni Marfia, Laura Riboni,