Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8301418 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2018 | 31 Pages |
Abstract
These data suggest formation of a product, 3-dehydro-4,6-deoxycholic acid, a recognized intermediate in the reductive arm of bile acid 7α-dehydroxylation pathway and the first report of a gene in the reductive arm of the bile acid 7α-dehydroxylating pathway.
Keywords
kiloDaltonLCMS-IT-TOFBSHBHICDCAAMUUHPLCDCAkDaESIIPTGBAILCAChenodeoxycholic acidDeoxycholic acidLithocholic acidCholic acidBile acidssodium dodecyl sulfate-polyacrylamide gel electrophoresisSDS-PAGEisopropyl β-D-1-thiogalactopyranosidebrain heart infusionFlavoproteinlysogeny brothBile salt hydrolaseatomic mass unitsUltra-high performance liquid chromatographyClostridiumelectrospray ionization
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Authors
Spencer C. Harris, Saravanan Devendran, João M.P. Alves, Sean M. Mythen, Phillip B. Hylemon, Jason M. Ridlon,