Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8301820 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2015 | 60 Pages |
Abstract
In conclusion, few models on cholesterol metabolism are able to pass a functional test. Apparently most models have not undergone the critical iterative systems biology cycle of validation. We expect modeling of cholesterol metabolism to go through many more model topologies and iterative cycles and welcome the increased understanding of cholesterol metabolism these are likely to bring.
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Authors
Yared Paalvast, Jan Albert Kuivenhoven, Albert K. Groen,