Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8302221 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2014 | 11 Pages |
Abstract
Targeting StarD3 may increase circulating levels of HDL and protect the liver against lipotoxicity; loss of hepatic expression of this protein, induced by genetic obesity, may contribute to the pathogenesis of dyslipidaemia and steatosis.
Keywords
HDLNAFLDMLN64Rplp1LDHAIGFBPIRS1HPRT1STARDb2mSREBPCYP2E1VLDLFXRGLUT1PGC-1αGAPDHABCA1ApoA-IATP binding cassette transporter A1farnesoid X receptorApolipoprotein A-INon-alcoholic steatohepatitisbeta-actinnon-alcoholic fatty liver diseaseSteatosisDyslipidaemiaMentalinsulin receptor substrate 1Starcytochrome P450 2E1ActbLactate dehydrogenase Ahigh density lipoproteinvery low density lipoproteinlow density lipoproteinLDLLipid metabolismInsulin resistanceBeta-2 microglobulinNash Hypoxanthine phosphoribosyltransferase 1sterol regulatory element binding proteinglucose transporter 1glyceraldehyde-3-phosphate dehydrogenase
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Authors
Ugo Soffientini, Anna-Maria Caridis, Sharron Dolan, Annette Graham,