| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8302281 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2014 | 7 Pages |
Abstract
These studies indicate that missense mutations Y528H, R540C, and N649S appear to cause ABL by reducing MTTP activity rather than by reducing binding of MTTP with protein disulfide isomerase or apoB. The region of MTTP containing amino acids 528 and 540 constitutes a critical domain for its lipid-transfer activity.
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Authors
Sharon A. Miller, John R. Burnett, Mike A. Leonis, C. James McKnight, Frank M. van Bockxmeer, Amanda J. Hooper,