| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8302610 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2013 | 9 Pages |
Abstract
Altogether, these results indicate that α-MSH-activated MC5R regulates two tightly coupled pathways in adipocytes: lipolysis and re-esterification. The global effect is a decrease in adipocyte fat mass, which is important for strategies to ameliorate obesity.
Keywords
ACCMSHMelanocortin 5 receptorHSLNEFAMCRsAMPKPEPCKpro-opiomelanocortinPLIN1pKaMC5RPOMCERKMAPKSmall interfering RNAsiRNAadenosine 5′-monophosphate-activated protein kinaseAdipocyteAtglacetyl-CoA carboxylasenonesterified fatty acidphosphoenolpyruvate carboxykinaseadipose triglyceride lipasehormone-sensitive lipaseLipolysisMelanocortinsMelanocyte-stimulating hormoneprotein kinase Amitogen-activated protein kinaseextracellular-regulated protein kinasePerilipin 1melanocortin receptors
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Authors
Adriana R. Rodrigues, Henrique Almeida, Alexandra M. Gouveia,