| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8302656 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2013 | 15 Pages |
Abstract
⺠Overexpression of YY1 induces hepatic steatosis in zebrafish. ⺠YY1 alters the expression of 16 hepatic genes associated with lipid metabolism. ⺠YY1 induces C/EBP-α and PPAR-γ expression by suppressing CHOP-10 expression. ⺠Overexpression of YY1 increases the gene expression of de novo FA synthesis. ⺠Overexpression of YY1 increases hepatic lipotoxicity and liver injury.
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Authors
Guor Mour Her, Wan-Yu Pai, Chi-Yu Lai, Yang-Wen Hsieh, Hsi-Wen Pang,