| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8302742 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2013 | 9 Pages |
Abstract
⺠In a new model lacking lipoprotein lipase (LPL) selectively in adipocytes, ⺠the absence of LPL leads to increased de novo lipogenesis in adipose tissue, ⺠the production of the anti-inflammatory fatty acid palmitoleate and ⺠mild metabolic improvements which are independent of white adipose tissue browning.
Keywords
COX-2DNLTRLChREBPLPLSCD1GLUT4GPIHBP1ACACABATHFDIWATELOVLDIO2PGC1aTBPFPLCSREBP1cgWATUcp1de novo lipogenesisFatty acidPolyunsaturated fatty acidsfatty acid synthasePUFAFatty acid elongaseWhite adipose tissuebrown adipose tissueTriglyceridesglucose transporter 4standard error of meanhigh-fat dietCyclooxygenase-2fast performance liquid chromatographyFasnLipoprotein lipasetriglyceride-rich lipoproteinsSEMObesityInsulin resistancewild typeTATA box binding proteincarbohydrate response element binding proteinSterol regulatory element binding protein 1cuncoupling protein 1WAT
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Authors
Alexander Bartelt, Clara Weigelt, M. Lisa Cherradi, Andreas Niemeier, Klaus Tödter, Joerg Heeren, Ludger Scheja,