| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8302743 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2013 | 7 Pages |
Abstract
⺠We discuss molecular and biochemical parameters of recruitment of brown and brite fat. ⺠UCP1 mRNA levels yield confounding indications of the degree of recruitment. ⺠Similarly, specific UCP1 protein levels (i.e. per mg protein) are not adequates. ⺠Only total UCP1 protein per depot/animal correlates with thermogenic capacity. ⺠Relative UCP1 mRNA increases in brite fat are extremely high but thermogenic capacity comparatively low.
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Authors
Jan Nedergaard, Barbara Cannon,