Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8302913 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2013 | 13 Pages |
Abstract
⺠ABC cholesterol transporters are differentially expressed in neurons and astroglia. ⺠ABCA1/ABCG1 induction increases cholesterol efflux from glia but not from neurons. ⺠ABCA1 silencing and inhibition reduce cholesterol efflux from glia but not neurons. ⺠ABCG1 silencing inhibits cholesterol efflux from astrocytes but not from neurons. ⺠ABCG4 silencing reduces cholesterol efflux from neurons but not from astrocytes.
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Authors
Jing Chen, Xiaolu Zhang, Handojo Kusumo, Lucio G. Costa, Marina Guizzetti,