| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8302929 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2013 | 8 Pages |
Abstract
⺠Common effect of polyunsaturated fatty acids (PUFAs) on breast cancer properties. ⺠Transient suppression of Akt phosphorylation by many PUFAs. ⺠Uniquely sustained suppression of Akt phosphorylation by docosahexaenoic acid (DHA). ⺠Unique suppression of deregulated growth of cancer cells by DHA.
Keywords
PDGFPLDFGFRDNA-PKSFARTKMUFAFFAmTORPDK1iGFRAktFree fatty acidsaturated fatty acidPolyunsaturated fatty acidsmonounsaturated fatty acidPolyunsaturated fatty acidPUFADocosahexaenoic acidsFatty acidsILKdiacylglycerolDAGBreast cancerplatelet-derived growth factorPhospholipase Dmammalian target of rapamycinphosphoinositide-dependent kinase 1DNA-dependent protein kinaseVitamin Eintegrin-linked kinaseReceptor Tyrosine Kinasefibroblast growth factor receptorInsulin-like growth factor receptor
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Authors
Satoshi B. Sato, Jungha Park, Jun Kawamoto, Sho Sato, Tatsuo Kurihara,