Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8303015 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 7 Pages |
Abstract
⺠MAFP inhibits the lipase, phospholipase and galactolipase activities of HPLRP2. ⺠MAFP therefore inhibits both phospholipase A1 (HPLRP2) and A2 (cPLA2) activities. ⺠These findings provide additional evidence that MAFP specificity is weak. ⺠These findings challenge the common use of MAFP as an inhibitor of PLA2s.
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Authors
Sawsan Amara, Vincent Delorme, Michel Record, Frédéric Carrière,