| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8303018 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 12 Pages |
Abstract
⺠LPA receptor antagonist DGPP 8:0 stimulates ERK1/2 by unknown mechanism. ⺠DGPP effect is not mediated by LPA receptors. ⺠Lipid phosphate phosphatase dephoshporylates DGPP. ⺠LPA receptor antagonist VPC32183 inhibits DGPP dephosphorylation. ⺠LPP1 siRNA or VPC32183 suppresses DGPP-induced ERK1/2 activation.
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Authors
Pierre-Christian Violet, Emmanuelle Billon-Denis, Philippe Robin,