Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8303056 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 9 Pages |
Abstract
⺠Conjugated linolenic acid is a linolenic acid isomer with a conjugated triene system. ⺠Conjugated linolenic acid had a strong cytotoxic effect in tumor cells. ⺠Conjugated linolenic acid induced apoptosis via lipid peroxidation. ⺠Cytotoxic effects of fatty acids were dependent on intracellular incorporation. ⺠Jacaric acid had a strong preventive antitumor effect in vivo.
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Authors
Nahoko Shinohara, Tsuyoshi Tsuduki, Junya Ito, Taro Honma, Ryo Kijima, Soko Sugawara, Tatsuya Arai, Masao Yamasaki, Aya Ikezaki, Marino Yokoyama, Kazuo Nishiyama, Kiyotaka Nakagawa, Teruo Miyazawa, Ikuo Ikeda,