| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8303077 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 12 Pages |
Abstract
⺠Ligands for RARs promoted cholesterol efflux from macrophages by increasing ABCA1/G1. ⺠RARs regulated ABCG1 transcription driven by dual promoters. ⺠Its transcription involved LXR-responsive element-dependent pathways. ⺠RARα activated ABCG1 promoter by binding to LXR-responsive element.
Keywords
ABCA1LXRRARRetinoid X receptorRXRABCG18-br-cAMP9cRAApoA-I9-Cis-retinoic acidLXREGAPDHHDLSULT2B1FBSDMEMTTNPBAcLDLATP-binding cassette transporter A1atRABSAATP-binding cassette transporter G1high-density lipoproteinDulbecco's modified Eagle's mediumall-trans retinoic acidbovine serum albuminApolipoprotein A-Idirect repeatCholesterol effluxfetal bovine serumacetylated low-density lipoproteinliver X receptorglyceraldehyde-3-phosphate dehydrogenaseRetinoic acid receptor
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Authors
Makoto Ayaori, Emi Yakushiji, Masatsune Ogura, Kazuhiro Nakaya, Tetsuya Hisada, Harumi Uto-Kondo, Shunichi Takiguchi, Yoshio Terao, Makoto Sasaki, Tomohiro Komatsu, Maki Iizuka, Makiko Yogo, Yoshinari Uehara, Hiroyuki Kagechika, Tsuyoshi Nakanishi,