| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8303087 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 6 Pages |
Abstract
⺠LCAT is a major modulator of HDL metabolism. ⺠Complete LCAT deficiency causes profound low HDL and modest hypertriglyceridemia. ⺠The role of LCAT in atherosclerosis remains controversial despite the dyslipidemia. ⺠Recent animal model studies revealed novel protective metabolic phenotypes. ⺠LCAT null mice are more insulin sensitive and resists diet induced obesity.
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Authors
Dominic S. Ng,