| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8303125 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 13 Pages |
Abstract
⺠RXRs are promiscuous partners in heterodimers with other nuclear receptors. ⺠Permissive heterodimers are responsive to ligands of each partner. ⺠Ligand structure is linked to cofactor interactions and physiological function. ⺠Rexinoids are promising drugs for the treatment of the Metabolic Syndrome. ⺠RXR/PPARγ and RXR/LXR heterodimer-specific rexinoids have been developed.
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Authors
Efrén Pérez, William Bourguet, Hinrich Gronemeyer, Angel R. de Lera,