Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8303140 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 11 Pages |
Abstract
⺠For the maintenance of constant vitamin A supply retinyl ester hydrolases are required. ⺠This review summarizes the current knowledge on the roles of retinyl ester hydrolyses in vitamin A metabolism. ⺠In addition, it discusses tissue-specific functions of retinyl ester hydrolases and highlights major gaps in the understanding of retinyl ester catabolism.
Keywords
CRBP1HSLLRATTIP47HSCVLDLHSPGLPLLRP-1CGI-58RBP4STRA6GS2chylomicronRPESTSDGAT1ES2CelmGlPTLPLRP2GPIHBP1monoacylglycerolPNPLAARATRehAtglSteroid sulfataseFatty acidretinal pigment epitheliumCESMobilizationtriacylglycerolRetinoic acidretinyl esterRetinyl ester hydrolaseBBBHepatic stellate cellendoplasmic reticulumStorePhospholipidlipid dropletlecithin:retinol acyltransferasePancreatic triglyceride lipaseadipose triglyceride lipasehormone-sensitive lipaseMonoglyceride lipasehepatic lipaseCarboxyl ester lipaseLipoprotein lipasevery low-density lipoproteinneutral lipidblood-brain-barrierknock-outwild-typeHeparan sulphate proteoglycanVitamin ARetinol-binding protein 4Pancreatic lipase-related protein 2carboxylesterasecholesteryl ester
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Authors
Renate Schreiber, Ulrike Taschler, Karina Preiss-Landl, Nuttaporn Wongsiriroj, Robert Zimmermann, Achim Lass,