| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8303187 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 7 Pages |
Abstract
⺠T3 regulates CrabpI gene in a bimodal fashion during adipocyte differentiation. ⺠TRAP220 is responsible for T3 activation of CrabpI gene in preadipocyte. ⺠RIP140 is responsible for T3 repression of CrabpI gene in differentiating adipocyte. ⺠Epigenetic regulation of CrabpI gene involves chromatin folding and nucleosome rearrangement on its regulatory region. ⺠Chromatin remodeling underlies epigenetic regulation of CrabpI gene during adipocyte differentiation.
Keywords
CRABPCRABPITRAP220RIP140MNaseLM-PCRTISRARchromatin immunoprecipitationChromatin remodelingRetinoic acidTranscription initiation siteTREchromosome conformation captureThyroid hormone response elementmicrococcal nucleaseThyroid hormonecellular retinoic acid binding proteinCHiPEmbryonal carcinomaRetinoic acid receptorthyroid hormone receptorReceptor interacting protein 140
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Authors
Li-Na Wei,