Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8303202 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2012 | 7 Pages |
Abstract
⺠PKCδ, p66Shc, cytochrome C and vitamin A form a mitochondrial signal module. ⺠The PKCδ signalosome senses and adjusts the workload of the respiratory chain. ⺠The PKCδ signalosome signals the pyruvate dehydrogenase complex to adjust fuel flux. ⺠Vitamin A serves as co-factor and electron carrier for redox activation of PKCδ.
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Authors
Beatrice Hoyos, Rebeca Acin-Perez, Donald A. Fischman, Giovanni Manfredi, Ulrich Hammerling,