Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8303212 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2011 | 7 Pages |
Abstract
⺠StAsp-PSI cytotoxicity requires disulfide bounds and negative charge phospholipids. ⺠Oligomerization of StAsp-PSI is necessary for its cytotoxic activity. ⺠StAsp-PSI cytotoxicity is inhibited by cholesterol.
Keywords
CHOLEPCEPA5-CarboxyfluoresceinTPEDTTSAPLIPPSITFEPCDMLV2,2,2-trifluoroethanolmultilamellar vesiclesegg phosphatidic acidepglarge unilamellar vesiclesMembrane destabilizationegg l-α-phosphatidylcholinedithiothreitolcircular dichroismLUVSUVProgrammed cell deathAspartic proteasesantimicrobial proteinSaposin-like proteinscholesterolsmall unilamellar vesiclesStap
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Authors
Fernando Muñoz, M. Francisca Palomares-Jerez, Gustavo Daleo, José VillalaÃn, M. Gabriela Guevara,