| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8303222 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2011 | 12 Pages |
Abstract
⺠A pool of brain BRSK1, but not BRSK2 or LKB1, localizes at membrane lipid rafts. ⺠Brain BRSK1 is palmitoylated. ⺠Raft-associated BRSK1 has higher activity than BRSK1 from non-raft environment. ⺠Small multilamellar vesicles made with lipids from rafts enhance BRSK1 activity. ⺠BRSK1-raft interaction: a new activating mechanism additional to LKB1 phosphorylation.
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Authors
Arantza RodrÃguez-Asiain, Gerard Ruiz-Babot, Walter Romero, Roger CubÃ, Tatiana Erazo, Ricardo M. Biondi, Jose R. Bayascas, Jose Aguilera, Nestor Gómez, Carles Gil, Enrique Claro, Jose M. Lizcano,