| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8303231 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2011 | 13 Pages |
Abstract
⺠N-Acylethanolamine (NAE) plasmalogens are precursors of NAEs in the brain. ⺠The phospholipase D-type enzyme NAPE-PLD converted NAE plasmalogen to NAE. ⺠Brain homogenates of NAPE-PLD-null mice also formed NAE from NAE plasmalogen. ⺠The homogenates could hydrolyze N-acylated plasmalogen lysophospholipids to NAEs. ⺠Thus NAPE-PLD-independent formation of NAEs from NAE plasmalogens was also shown.
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Authors
Kazuhito Tsuboi, Yasuo Okamoto, Natsuki Ikematsu, Manami Inoue, Yoshibumi Shimizu, Toru Uyama, Jun Wang, Dale G. Deutsch, Matthew P. Burns, Nadine M. Ulloa, Akira Tokumura, Natsuo Ueda,