Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8303235 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2011 | 10 Pages |
Abstract
⺠A novel dolichol phosphate was identified in the thermoacidophilic archaeon, Sulfolobus acidocaldarius using LC-ESI/MS/MS. ⺠The unusually short S. acidocaldarius dolichol phosphate presents a degree of saturation not previously reported. ⺠S. acidocaldarius dolichol phosphate α- and Ï-position isoprenes are saturated, as are intra-chain isoprenes. ⺠Hexose-charged dolichol phosphate species were also detected.
Keywords
CIDDOXPDeoxyxylulose phosphateUNDPSulfolobus acidocaldariusGeranylgeranyl reductaseCPDsCHCl3GGPPIPPMRMDMAPPMevalonateMS/MSCollision-induced dissociationAcetateElectrospray Ionization Mass Spectrometryisopentenyl diphosphateGGRArchaeaDolichyl phosphateDolicholdimethylallyl diphosphateTandem mass spectrometryMVAMethanolMeOHmultiple reaction monitoringPolyprenolChloroformgeranylgeranyl diphosphate
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Authors
Ziqiang Guan, Benjamin H. Meyer, Sonja-Verena Albers, Jerry Eichler,