| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8303237 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2011 | 8 Pages |
Abstract
⺠Adiponectin induces activin A and lowers its natural inhibitor follistatin in primary human hepatocytes. ⺠Palmitic and oleic acid increase TGFβ in primary human hepatocytes. ⺠Impaired adiponectin signaling in fat loaded cells is related to increased TGFβ. ⺠Systemic adiponectin but not activin A and follistatin are significantly reduced in patients with fatty liver.
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Authors
Josef Wanninger, Markus Neumeier, Claus Hellerbrand, Doris Schacherer, Sabrina Bauer, Thomas S. Weiss, Hanna Huber, Andreas Schäffler, Charalampos Aslanidis, Jürgen Schölmerich, Christa Buechler,